The Best NAD Dosage For Longevity
NMN (nicotinamide riboside) is the direct precursor to nicotinamide adenine dinucleotide (NAD), an important coenzyme involved in many cellular functions. This includes cell signaling, metabolism, and DNA repair. A growing number of studies show that boosting NAD levels with nmn supplements can have positive effects on health and longevity.
Is NMN toxic to the liver?
The best nmn dosage depends on the desired effect and health condition. In general, 250-500 mg per day is considered safe. NMN is easily absorbed into the body and is available in oral forms, such as capsules or powders. Some products are also available as sublingual tablets that dissolve under the tongue for fast absorption. Intranasal delivery may offer even greater bioavailability.
In addition to increasing energy levels, NMN can also improve insulin sensitivity and promote weight loss. In one clinical trial, postmenopausal women with prediabetes were given daily NMN at doses of 300mg, 600mg and 900mg to measure the impact on blood NAD+ levels and physical performance. The results showed that 600mg NMN was optimal for increasing NAD+ levels and improving metabolic function.
NAD levels naturally decrease with age, with 50-year-olds having about half the levels of 20-year-olds. High NAD levels activate sirtuins, which can reduce oxidative stress and extend lifespan. NMN is an effective NAD booster that can be used in combination with other supplements, including sirtuin activators and resveratrol. Scientists are excited about its potential to extend healthspan, but further studies are needed to determine if it is an effective anti-aging treatment.